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Rational Design and Adaptive Management of Combination Therapies for Hepatitis C Virus Infection

Recent discoveries of direct acting antivirals against Hepatitis C virus (HCV) have raised hopes of effective treatment via combination therapies. Yet rapid evolution and high diversity of HCV populations, combined with the reality of suboptimal treatment adherence, make drug resistance a clinical a...

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Detalles Bibliográficos
Autores principales:	Ke, Ruian, Loverdo, Claude, Qi, Hangfei, Sun, Ren, Lloyd-Smith, James O.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4488346/ https://www.ncbi.nlm.nih.gov/pubmed/26125950 http://dx.doi.org/10.1371/journal.pcbi.1004040

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