The effects analysis of two neonicotinoid insecticides on in vitro maturation of porcine oocytes using hanging drop monoculture method

Acetamiprid (ACE) and imidacroprid (IMI) are known neonicotinoid insecticides with strong affinities for the insect-selective nicotinic acetylcholine receptor. These provide insect control by hyperstimulating insect nerves and are used for agricultural pest management. However, it has also been repo...

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Autores principales: ISHIKAWA, Sadamasa, HIRAGA, Kou, HIRADATE, Yuuki, TANEMURA, Kentaro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Society of Veterinary Science 2015
Materias:
Anatomy
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4488412/
https://www.ncbi.nlm.nih.gov/pubmed/25715671
http://dx.doi.org/10.1292/jvms.15-0008
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author ISHIKAWA, Sadamasa
HIRAGA, Kou
HIRADATE, Yuuki
TANEMURA, Kentaro
author_facet ISHIKAWA, Sadamasa
HIRAGA, Kou
HIRADATE, Yuuki
TANEMURA, Kentaro
author_sort ISHIKAWA, Sadamasa
collection PubMed
description Acetamiprid (ACE) and imidacroprid (IMI) are known neonicotinoid insecticides with strong affinities for the insect-selective nicotinic acetylcholine receptor. These provide insect control by hyperstimulating insect nerves and are used for agricultural pest management. However, it has also been reported that ACE and IMI affect mammalian reproductive function. We determined the effects of ACE and IMI on the in vitro maturation of porcine oocytes. Significant decreases in nuclear maturation rates were observed in the ACE or IMI-exposed groups. Also, in matured oocytes from the ACE or IMI-exposed groups, irregular chromosomes were observed. Our results suggest that ACE and IMI exposure was detrimental to porcine oocytes and the extent of the effects depends on the concentration of exposure.
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spelling pubmed-44884122015-07-06 The effects analysis of two neonicotinoid insecticides on in vitro maturation of porcine oocytes using hanging drop monoculture method ISHIKAWA, Sadamasa HIRAGA, Kou HIRADATE, Yuuki TANEMURA, Kentaro J Vet Med Sci Anatomy Acetamiprid (ACE) and imidacroprid (IMI) are known neonicotinoid insecticides with strong affinities for the insect-selective nicotinic acetylcholine receptor. These provide insect control by hyperstimulating insect nerves and are used for agricultural pest management. However, it has also been reported that ACE and IMI affect mammalian reproductive function. We determined the effects of ACE and IMI on the in vitro maturation of porcine oocytes. Significant decreases in nuclear maturation rates were observed in the ACE or IMI-exposed groups. Also, in matured oocytes from the ACE or IMI-exposed groups, irregular chromosomes were observed. Our results suggest that ACE and IMI exposure was detrimental to porcine oocytes and the extent of the effects depends on the concentration of exposure. The Japanese Society of Veterinary Science 2015-02-06 2015-06 /pmc/articles/PMC4488412/ /pubmed/25715671 http://dx.doi.org/10.1292/jvms.15-0008 Text en ©2015 The Japanese Society of Veterinary Science http://creativecommons.org/licenses/by-nc-nd/3.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution Non-Commercial No Derivatives (by-nc-nd) License.
spellingShingle Anatomy
ISHIKAWA, Sadamasa
HIRAGA, Kou
HIRADATE, Yuuki
TANEMURA, Kentaro
The effects analysis of two neonicotinoid insecticides on in vitro maturation of porcine oocytes using hanging drop monoculture method
title The effects analysis of two neonicotinoid insecticides on in vitro maturation of porcine oocytes using hanging drop monoculture method
title_full The effects analysis of two neonicotinoid insecticides on in vitro maturation of porcine oocytes using hanging drop monoculture method
title_fullStr The effects analysis of two neonicotinoid insecticides on in vitro maturation of porcine oocytes using hanging drop monoculture method
title_full_unstemmed The effects analysis of two neonicotinoid insecticides on in vitro maturation of porcine oocytes using hanging drop monoculture method
title_short The effects analysis of two neonicotinoid insecticides on in vitro maturation of porcine oocytes using hanging drop monoculture method
title_sort effects analysis of two neonicotinoid insecticides on in vitro maturation of porcine oocytes using hanging drop monoculture method
topic Anatomy
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4488412/
https://www.ncbi.nlm.nih.gov/pubmed/25715671
http://dx.doi.org/10.1292/jvms.15-0008
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