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An Efficient Method for Identifying Gene Fusions by Targeted RNA Sequencing from Fresh Frozen and FFPE Samples
Fusion genes are known to be key drivers of tumor growth in several types of cancer. Traditionally, detecting fusion genes has been a difficult task based on fluorescent in situ hybridization to detect chromosomal abnormalities. More recently, RNA sequencing has enabled an increased pace of fusion g...
Autores principales: | Scolnick, Jonathan A., Dimon, Michelle, Wang, I-Ching, Huelga, Stephanie C., Amorese, Douglas A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4488430/ https://www.ncbi.nlm.nih.gov/pubmed/26132974 http://dx.doi.org/10.1371/journal.pone.0128916 |
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