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Design Rationale and Development Approach for Pegfilgrastim as a Long-Acting Granulocyte Colony-Stimulating Factor

Filgrastim, a recombinant methionyl human granulocyte colony-stimulating factor (G-CSF) (r-metHuG-CSF), is efficacious in stimulating neutrophil production and maturation to prevent febrile neutropenia (FN) in response to chemotherapy. Because of its relatively short circulating half-life, daily fil...

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Detalles Bibliográficos
Autores principales:	Arvedson, Tara, O’Kelly, James, Yang, Bing-Bing
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer International Publishing 2015
Materias:	Review Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4488452/ https://www.ncbi.nlm.nih.gov/pubmed/25998211 http://dx.doi.org/10.1007/s40259-015-0127-4

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