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Dendritic Cell-Mediated Phagocytosis but Not Immune Activation Is Enhanced by Plasmin
Removal of dead cells in the absence of concomitant immune stimulation is essential for tissue homeostasis. We recently identified an injury-induced protein misfolding event that orchestrates the plasmin-dependent proteolytic degradation of necrotic cells. As impaired clearance of dead cells by the...
Autores principales: | Borg, Rachael J., Samson, Andre L., Au, Amanda E.-L., Scholzen, Anja, Fuchsberger, Martina, Kong, Ying Y., Freeman, Roxann, Mifsud, Nicole A., Plebanski, Magdalena, Medcalf, Robert L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4488505/ https://www.ncbi.nlm.nih.gov/pubmed/26132730 http://dx.doi.org/10.1371/journal.pone.0131216 |
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