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B-Lymphocyte Depletion in Myalgic Encephalopathy/ Chronic Fatigue Syndrome. An Open-Label Phase II Study with Rituximab Maintenance Treatment

BACKGROUND: Myalgic Encephalopathy/Chronic Fatigue Syndrome (ME/CFS) is a disease of unknown etiology. We previously reported a pilot case series followed by a small, randomized, placebo-controlled phase II study, suggesting that B-cell depletion using the monoclonal anti-CD20 antibody rituximab can...

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Detalles Bibliográficos
Autores principales: Fluge, Øystein, Risa, Kristin, Lunde, Sigrid, Alme, Kine, Rekeland, Ingrid Gurvin, Sapkota, Dipak, Kristoffersen, Einar Kleboe, Sørland, Kari, Bruland, Ove, Dahl, Olav, Mella, Olav
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4488509/
https://www.ncbi.nlm.nih.gov/pubmed/26132314
http://dx.doi.org/10.1371/journal.pone.0129898