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Hormonal status and age differentially affect tolerance to the disruptive effects of delta-9-tetrahydrocannabinol (Δ(9)-THC) on learning in female rats
The effects of hormone status and age on the development of tolerance to Δ(9)-THC were assessed in sham-operated (intact) or ovariectomized (OVX) female rats that received either intraperitoneal saline or 5.6 mg/kg of Δ(9)-THC daily from postnatal day (PD) 75–180 (early adulthood onward) or PD 35–14...
Autores principales: | Winsauer, Peter J., Filipeanu, Catalin M., Weed, Peter F., Sutton, Jessie L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4488627/ https://www.ncbi.nlm.nih.gov/pubmed/26191005 http://dx.doi.org/10.3389/fphar.2015.00133 |
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