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EMAST is a Form of Microsatellite Instability That is Initiated by Inflammation and Modulates Colorectal Cancer Progression

DNA mismatch repair (MMR) function is critical for correcting errors coincident with polymerase-driven DNA replication, and its proteins are frequent targets for inactivation (germline or somatic), generating a hypermutable tumor that drives cancer progression. The biomarker for defective DNA MMR is...

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Detalles Bibliográficos
Autores principales:	Carethers, John M., Koi, Minoru, Tseng-Rogenski, Stephanie S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2015
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4488660/ https://www.ncbi.nlm.nih.gov/pubmed/25836926 http://dx.doi.org/10.3390/genes6020185

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