The Fork in the Road: Histone Partitioning During DNA Replication

In the following discussion the distribution of histones at the replication fork is examined, with specific attention paid to the question of H3/H4 tetramer "splitting." After a presentation of early experiments surrounding this topic, more recent contributions are detailed. The implicatio...

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Detalles Bibliográficos
Autor principal: Annunziato, Anthony T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4488668/
https://www.ncbi.nlm.nih.gov/pubmed/26110314
http://dx.doi.org/10.3390/genes6020353
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author Annunziato, Anthony T.
author_facet Annunziato, Anthony T.
author_sort Annunziato, Anthony T.
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description In the following discussion the distribution of histones at the replication fork is examined, with specific attention paid to the question of H3/H4 tetramer "splitting." After a presentation of early experiments surrounding this topic, more recent contributions are detailed. The implications of these findings with respect to the transmission of histone modifications and epigenetic models are also addressed.
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spelling pubmed-44886682015-07-02 The Fork in the Road: Histone Partitioning During DNA Replication Annunziato, Anthony T. Genes (Basel) Review In the following discussion the distribution of histones at the replication fork is examined, with specific attention paid to the question of H3/H4 tetramer "splitting." After a presentation of early experiments surrounding this topic, more recent contributions are detailed. The implications of these findings with respect to the transmission of histone modifications and epigenetic models are also addressed. MDPI 2015-06-23 /pmc/articles/PMC4488668/ /pubmed/26110314 http://dx.doi.org/10.3390/genes6020353 Text en © 2015 by the authors; licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Annunziato, Anthony T.
The Fork in the Road: Histone Partitioning During DNA Replication
title The Fork in the Road: Histone Partitioning During DNA Replication
title_full The Fork in the Road: Histone Partitioning During DNA Replication
title_fullStr The Fork in the Road: Histone Partitioning During DNA Replication
title_full_unstemmed The Fork in the Road: Histone Partitioning During DNA Replication
title_short The Fork in the Road: Histone Partitioning During DNA Replication
title_sort fork in the road: histone partitioning during dna replication
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4488668/
https://www.ncbi.nlm.nih.gov/pubmed/26110314
http://dx.doi.org/10.3390/genes6020353
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