Reduced Toxicity of Shiga Toxin (Stx) Type 2c in Mice Compared to Stx2d Is Associated with Instability of Stx2c Holotoxin

Shiga toxin (Stx) is an AB(5) ribotoxin made by Stx-producing Escherichia coli (STEC). These organisms cause diarrhea, hemorrhagic colitis and the hemolytic uremic syndrome. STEC make two types of Stxs, Stx1 and/or Stx2. Stx2 has one prototype (a) and six subtypes (b–g), but only STEC that make Stx2...

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Detalles Bibliográficos
Autores principales: Bunger, Joshua C., Melton-Celsa, Angela R., Maynard, Ernest L., O’Brien, Alison D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4488704/
https://www.ncbi.nlm.nih.gov/pubmed/26110507
http://dx.doi.org/10.3390/toxins7062306

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4488704/
https://www.ncbi.nlm.nih.gov/pubmed/26110507
http://dx.doi.org/10.3390/toxins7062306

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