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Recombinant Immunomodulating Lentogenic or Mesogenic Oncolytic Newcastle Disease Virus for Treatment of Pancreatic Adenocarcinoma

Oncolytic Newcastle disease virus (NDV) might be a promising new therapeutic agent for the treatment of pancreatic cancer. We evaluated recombinant NDVs (rNDVs) expressing interferon (rNDV-hIFNβ-F(0)) or an IFN antagonistic protein (rNDV-NS1-F(0)), as well as rNDV with increased virulence (rNDV-F(3a...

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Detalles Bibliográficos
Autores principales:	Buijs, Pascal, van Nieuwkoop, Stefan, Vaes, Vincent, Fouchier, Ron, van Eijck, Casper, van den Hoogen, Bernadette
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2015
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4488723/ https://www.ncbi.nlm.nih.gov/pubmed/26110582 http://dx.doi.org/10.3390/v7062756

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