A Novel Chimeric Anti-PA Neutralizing Antibody for Postexposure Prophylaxis and Treatment of Anthrax

Anthrax is a highly lethal infectious disease caused by the bacterium Bacillus anthracis, and the associated shock is closely related to the lethal toxin (LeTx) produced by the bacterium. The central role played by the 63 kDa protective antigen (PA63) region of LeTx in the pathophysiology of anthrax...

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Detalles Bibliográficos
Autores principales: Xiong, Siping, Tang, Qi, Liang, Xudong, Zhou, Tingting, Yang, Jin, Liu, Peng, Chen, Ya, Wang, Changjun, Feng, Zhenqing, Zhu, Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4488766/
https://www.ncbi.nlm.nih.gov/pubmed/26134518
http://dx.doi.org/10.1038/srep11776

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