Exome Analyses of Long QT Syndrome Reveal Candidate Pathogenic Mutations in Calmodulin-Interacting Genes

Long QT syndrome (LQTS) is an arrhythmogenic disorder that can lead to sudden death. To date, mutations in 15 LQTS-susceptibility genes have been implicated. However, the genetic cause for approximately 20% of LQTS patients remains elusive. Here, we performed whole-exome sequencing analyses on 59 LQ...

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Detalles Bibliográficos
Autores principales: Shigemizu, Daichi, Aiba, Takeshi, Nakagawa, Hidewaki, Ozaki, Kouichi, Miya, Fuyuki, Satake, Wataru, Toda, Tatsushi, Miyamoto, Yoshihiro, Fujimoto, Akihiro, Suzuki, Yutaka, Kubo, Michiaki, Tsunoda, Tatsuhiko, Shimizu, Wataru, Tanaka, Toshihiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4488844/
https://www.ncbi.nlm.nih.gov/pubmed/26132555
http://dx.doi.org/10.1371/journal.pone.0130329

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