Drug Metabolizing Enzyme and Transporter Gene Variation, Nicotine Metabolism, Prospective Abstinence, and Cigarette Consumption

The Nicotine Metabolite Ratio (NMR, ratio of trans-3’-hydroxycotinine and cotinine), has previously been associated with CYP2A6 activity, response to smoking cessation treatments, and cigarette consumption. We searched for drug metabolizing enzyme and transporter (DMET) gene variation associated wit...

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Detalles Bibliográficos
Autores principales: Bergen, Andrew W., Michel, Martha, Nishita, Denise, Krasnow, Ruth, Javitz, Harold S., Conneely, Karen N., Lessov-Schlaggar, Christina N., Hops, Hyman, Zhu, Andy Z. X., Baurley, James W., McClure, Jennifer B., Hall, Sharon M., Baker, Timothy B., Conti, David V., Benowitz, Neal L., Lerman, Caryn, Tyndale, Rachel F., Swan, Gary E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4488893/
https://www.ncbi.nlm.nih.gov/pubmed/26132489
http://dx.doi.org/10.1371/journal.pone.0126113

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