Haploid Genetic Screen Reveals a Profound and Direct Dependence on Cholesterol for Hantavirus Membrane Fusion

Hantaviruses cause hemorrhagic fever with renal syndrome (HFRS) in the Old World and a highly fatal hantavirus cardiopulmonary syndrome (HCPS) in the New World. No vaccines or antiviral therapies are currently available to prevent or treat hantavirus disease, and gaps in our understanding of how han...

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Detalles Bibliográficos
Autores principales: Kleinfelter, Lara M., Jangra, Rohit K., Jae, Lucas T., Herbert, Andrew S., Mittler, Eva, Stiles, Katie M., Wirchnianski, Ariel S., Kielian, Margaret, Brummelkamp, Thijn R., Dye, John M., Chandran, Kartik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Microbiology 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4488941/
https://www.ncbi.nlm.nih.gov/pubmed/26126854
http://dx.doi.org/10.1128/mBio.00801-15

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