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Human Urine Decreases Function and Expression of Type 1 Pili in Uropathogenic Escherichia coli

Uropathogenic Escherichia coli (UPEC) is the primary cause of community-acquired urinary tract infections (UTIs). UPEC bind the bladder using type 1 pili, encoded by the fim operon in nearly all E. coli. Assembled type 1 pili terminate in the FimH adhesin, which specifically binds to mannosylated gl...

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Detalles Bibliográficos
Autores principales:	Greene, Sarah E., Hibbing, Michael E., Janetka, James, Chen, Swaine L., Hultgren, Scott J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society of Microbiology 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4488945/ https://www.ncbi.nlm.nih.gov/pubmed/26126855 http://dx.doi.org/10.1128/mBio.00820-15

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