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Capturing coevolutionary signals inrepeat proteins

BACKGROUND: The analysis of correlations of amino acid occurrences in globular domains has led to the development of statistical tools that can identify native contacts – portions of the chains that come to close distance in folded structural ensembles. Here we introduce a direct coupling analysis f...

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Detalles Bibliográficos
Autores principales: Espada, Rocío, Parra, R Gonzalo, Mora, Thierry, Walczak, Aleksandra M, Ferreiro, Diego U
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4489039/
https://www.ncbi.nlm.nih.gov/pubmed/26134293
http://dx.doi.org/10.1186/s12859-015-0648-3