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A bioinformatic framework for immune repertoire diversity profiling enables detection of immunological status
BACKGROUND: Lymphocyte receptor repertoires are continually shaped throughout the lifetime of an individual in response to environmental and pathogenic exposure. Thus, they may serve as a fingerprint of an individual’s ongoing immunological status (e.g., healthy, infected, vaccinated), with far-reac...
Autores principales: | Greiff, Victor, Bhat, Pooja, Cook, Skylar C., Menzel, Ulrike, Kang, Wenjing, Reddy, Sai T. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4489130/ https://www.ncbi.nlm.nih.gov/pubmed/26140055 http://dx.doi.org/10.1186/s13073-015-0169-8 |
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