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Significance of filamin A in mTORC2 function in glioblastoma

BACKGROUND: Glioblastoma multiforme (GBM) is one of the most highly metastatic cancers. GBM has been associated with a high level of the mechanistic target of rapamycin complex 2 (mTORC2) activity. We aimed to observe roles of mTORC2 in GBM cells especially on actin cytoskeleton reorganization, cell...

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Detalles Bibliográficos
Autores principales:	Chantaravisoot, Naphat, Wongkongkathep, Piriya, Loo, Joseph A., Mischel, Paul S., Tamanoi, Fuyuhiko
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2015
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4489161/ https://www.ncbi.nlm.nih.gov/pubmed/26134617 http://dx.doi.org/10.1186/s12943-015-0396-z

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