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Assessing the impact of mutations found in next generation sequencing data over human signaling pathways
Modern sequencing technologies produce increasingly detailed data on genomic variation. However, conventional methods for relating either individual variants or mutated genes to phenotypes present known limitations given the complex, multigenic nature of many diseases or traits. Here we present PATH...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4489259/ https://www.ncbi.nlm.nih.gov/pubmed/25883139 http://dx.doi.org/10.1093/nar/gkv349 |