Unraveling Cholesterol Catabolism in Mycobacterium tuberculosis: ChsE4-ChsE5 α(2)β(2) Acyl-CoA Dehydrogenase Initiates β-Oxidation of 3-Oxo-cholest-4-en-26-oyl CoA

[Image: see text] The metabolism of host cholesterol by Mycobacterium tuberculosis (Mtb) is an important factor for both its virulence and pathogenesis, although how and why cholesterol metabolism is required is not fully understood. Mtb uses a unique set of catabolic enzymes that are homologous to...

Descripción completa

Detalles Bibliográficos
Autores principales: Yang, Meng, Lu, Rui, Guja, Kip E., Wipperman, Matthew F., St. Clair, Johnna R., Bonds, Amber C., Garcia-Diaz, Miguel, Sampson, Nicole S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2015
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4489319/
https://www.ncbi.nlm.nih.gov/pubmed/26161441
http://dx.doi.org/10.1021/id500033m

Ejemplares similares

Ejemplares similares