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Intracellular Transport Routes for MHC I and Their Relevance for Antigen Cross-Presentation
Cross-presentation, in which exogenous antigens are presented via MHC I complexes, is involved both in the generation of anti-infectious and anti-tumoral cytotoxic CD8(+) T cells and in the maintenance of immune tolerance. While cross-presentation was described almost four decades ago and while it i...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4489332/ https://www.ncbi.nlm.nih.gov/pubmed/26191062 http://dx.doi.org/10.3389/fimmu.2015.00335 |