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Structural Model of RNA Polymerase II Elongation Complex with Complete Transcription Bubble Reveals NTP Entry Routes

The RNA polymerase II (Pol II) is a eukaryotic enzyme that catalyzes the synthesis of the messenger RNA using a DNA template. Despite numerous biochemical and biophysical studies, it remains elusive whether the “secondary channel” is the only route for NTP to reach the active site of the enzyme or i...

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Detalles Bibliográficos
Autores principales:	Zhang, Lu, Silva, Daniel-Adriano, Pardo-Avila, Fátima, Wang, Dong, Huang, Xuhui
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4489626/ https://www.ncbi.nlm.nih.gov/pubmed/26134169 http://dx.doi.org/10.1371/journal.pcbi.1004354

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