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Role of the Sigma-1 receptor in Amyotrophic Lateral Sclerosis (ALS)

Amyotrophic Lateral Sclerosis (ALS) is a neurodegenerative disease affecting spinal cord motoneurons (MN) with an associative connection to Frontotemporal Lobar Dementia (FTLD). The endoplasmic reticulum (ER) bound Sigma-1 Receptor (S1R) chaperone protein localizes to specialized ER cisternae within...

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Detalles Bibliográficos
Autores principales:	Mavlyutov, Timur A., Guo, Lian-Wang, Epstein, Miles L., Ruoho, Arnold E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2015
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4489701/ https://www.ncbi.nlm.nih.gov/pubmed/25704013 http://dx.doi.org/10.1016/j.jphs.2014.12.013

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