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Herpesvirus Genome Recognition Induced Acetylation of Nuclear IFI16 Is Essential for Its Cytoplasmic Translocation, Inflammasome and IFN-β Responses

The IL-1β and type I interferon-β (IFN-β) molecules are important inflammatory cytokines elicited by the eukaryotic host as innate immune responses against invading pathogens and danger signals. Recently, a predominantly nuclear gamma-interferon-inducible protein 16 (IFI16) involved in transcription...

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Detalles Bibliográficos
Autores principales: Ansari, Mairaj Ahmed, Dutta, Sujoy, Veettil, Mohanan Valiya, Dutta, Dipanjan, Iqbal, Jawed, Kumar, Binod, Roy, Arunava, Chikoti, Leela, Singh, Vivek Vikram, Chandran, Bala
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4489722/
https://www.ncbi.nlm.nih.gov/pubmed/26134128
http://dx.doi.org/10.1371/journal.ppat.1005019

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