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γδ T Cells Are Required for M2 Macrophage Polarization and Resolution of Ozone-Induced Pulmonary Inflammation in Mice

We examined the role of γδ T cells in the induction of alternatively activated M2 macrophages and the resolution of inflammation after ozone exposure. Wildtype (WT) mice and mice deficient in γδ T cells (TCRδ(-/-) mice) were exposed to air or to ozone (0.3 ppm for up to 72h) and euthanized immediate...

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Detalles Bibliográficos
Autores principales:	Mathews, Joel A., Kasahara, David I., Ribeiro, Luiza, Wurmbrand, Allison P., Ninin, Fernanda M. C., Shore, Stephanie A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4489797/ https://www.ncbi.nlm.nih.gov/pubmed/26135595 http://dx.doi.org/10.1371/journal.pone.0131236

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