Reversibility of Defective Hematopoiesis Caused by Telomere Shortening in Telomerase Knockout Mice

Telomere shortening is common in bone marrow failure syndromes such as dyskeratosis congenita (DC), aplastic anemia (AA) and myelodysplastic syndromes (MDS). However, improved knowledge of the lineage-specific consequences of telomere erosion and restoration of telomere length in hematopoietic proge...

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Detalles Bibliográficos
Autores principales: Raval, Aparna, Behbehani, Gregory K., Nguyen, Le Xuan Truong, Thomas, Daniel, Kusler, Brenda, Garbuzov, Alina, Ramunas, John, Holbrook, Colin, Park, Christopher Y., Blau, Helen, Nolan, Garry P., Artandi, Steven E., Mitchell, Beverly S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4489842/
https://www.ncbi.nlm.nih.gov/pubmed/26133370
http://dx.doi.org/10.1371/journal.pone.0131722

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