Improved Structure and Function in Autosomal Recessive Polycystic Rat Kidneys with Renal Tubular Cell Therapy

Autosomal recessive polycystic kidney disease is a truly catastrophic monogenetic disease, causing death and end stage renal disease in neonates and children. Using PCK female rats, an orthologous model of autosomal recessive polycystic kidney disease harboring mutant Pkhd1, we tested the hypothesis...

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Detalles Bibliográficos
Autores principales: Kelly, K. J., Zhang, Jizhong, Han, Ling, Kamocka, Malgorzata, Miller, Caroline, Gattone, Vincent H., Dominguez, Jesus H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4489886/
https://www.ncbi.nlm.nih.gov/pubmed/26136112
http://dx.doi.org/10.1371/journal.pone.0131677

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