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2-Deoxy-d-Glucose Can Complement Doxorubicin and Sorafenib to Suppress the Growth of Papillary Thyroid Carcinoma Cells

Tumor cells display a shift in energy metabolism from oxidative phosphorylation to aerobic glycolysis. A subset of papillary thyroid carcinoma (PTC) is refractory to surgery and radioactive iodine ablation. Doxorubicin and sorafenib are the drugs of choice for treating advanced thyroid cancer but bo...

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Detalles Bibliográficos
Autores principales: Wang, Shuo-Yu, Wei, Yau-Huei, Shieh, Dar-Bin, Lin, Li-Ling, Cheng, Shih-Ping, Wang, Pei-Wen, Chuang, Jiin-Haur
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4489888/
https://www.ncbi.nlm.nih.gov/pubmed/26134286
http://dx.doi.org/10.1371/journal.pone.0130959