Low-molecular-weight chitosan scavenges methylglyoxal and N(ε)-(carboxyethyl)lysine, the major factors contributing to the pathogenesis of nephropathy

Methylglyoxal (MG) can cause protein glycation, resulting in cell damage and dysfunction. Accumulation of MG and its downstream metabolite N(ε)-(carboxyethyl)lysine (CEL) has been identified in several variations of nephropathy, including diabetic, hypertensive, and gentamicin-induced nephropathies....

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Detalles Bibliográficos
Autores principales: Chou, Chu-Kuang, Chen, Shih-Ming, Li, Yi-Chieh, Huang, Tzu-Chuan, Lee, Jen-Ai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4489968/
https://www.ncbi.nlm.nih.gov/pubmed/26155451
http://dx.doi.org/10.1186/s40064-015-1106-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4489968/
https://www.ncbi.nlm.nih.gov/pubmed/26155451
http://dx.doi.org/10.1186/s40064-015-1106-4

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