Cargando…

Low-molecular-weight chitosan scavenges methylglyoxal and N(ε)-(carboxyethyl)lysine, the major factors contributing to the pathogenesis of nephropathy

Methylglyoxal (MG) can cause protein glycation, resulting in cell damage and dysfunction. Accumulation of MG and its downstream metabolite N(ε)-(carboxyethyl)lysine (CEL) has been identified in several variations of nephropathy, including diabetic, hypertensive, and gentamicin-induced nephropathies....

Descripción completa

Detalles Bibliográficos
Autores principales:	Chou, Chu-Kuang, Chen, Shih-Ming, Li, Yi-Chieh, Huang, Tzu-Chuan, Lee, Jen-Ai
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer International Publishing 2015
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4489968/ https://www.ncbi.nlm.nih.gov/pubmed/26155451 http://dx.doi.org/10.1186/s40064-015-1106-4

Ejemplares similares

Free L-Lysine and Its Methyl Ester React with Glyoxal and Methylglyoxal in Phosphate Buffer (100 mM, pH 7.4) to Form N(ε)-Carboxymethyl-Lysine, N(ε)-Carboxyethyl-Lysine and N(ε)-Hydroxymethyl-Lysine
por: Baskal, Svetlana, et al.
Publicado: (2022)

Validation study to compare effects of processing protocols on measured N(ε)-(carboxymethyl)lysine and N(ε)-(carboxyethyl)lysine in blood
por: Hull, George L.J., et al.
Publicado: (2013)

Contents and Correlations of N(ε)-(carboxymethyl)lysine, N(ε)-(carboxyethyl)lysine, Acrylamide and Nutrients in Plant-Based Meat Analogs
por: Fu, Shuang, et al.
Publicado: (2023)

Formation of N(ε)-Carboxymethyl-Lysine and N(ε)-Carboxyethyl-Lysine in Pacific Oyster (Crassostrea gigas) Induced by Thermal Processing Methods
por: Zhou, Pengcheng, et al.
Publicado: (2022)

Unravelling the effect of N(ε)-(carboxyethyl)lysine on the conformation, dynamics and aggregation propensity of α-synuclein
por: Mariño, Laura, et al.
Publicado: (2020)

Formation of N(ε)-Carboxymethyl-Lysine and N(ε)-Carboxyethyl-Lysine in Heated Fish Myofibrillar Proteins with Glucose: Relationship with Its Protein Structural Characterization
por: Zhang, Siqi, et al.
Publicado: (2023)

Simultaneous Determination of N(ε)-(carboxymethyl) Lysine and N(ε)-(carboxyethyl) Lysine in Different Sections of Antler Velvet after Various Processing Methods by UPLC-MS/MS
por: Gong, Rui-ze, et al.
Publicado: (2018)

Methylglyoxal Scavengers Attenuate Angiogenesis Dysfunction Induced by Methylglyoxal and Oxygen-Glucose Deprivation
por: Chen, Wei, et al.
Publicado: (2022)

Characterization of the Deoxyguanosine–Lysine Cross-Link of Methylglyoxal
por: Petrova, Katya V., et al.
Publicado: (2014)

Structural and Functional Studies of S-(2-Carboxyethyl)-L-Cysteine and S-(2-Carboxyethyl)-l-Cysteine Sulfoxide
por: Waters, James K., et al.
Publicado: (2022)

Contribution of N(ε)-lysine Acetylation towards Regulation of Bacterial Pathogenesis
por: Luu, Jackson, et al.
Publicado: (2021)

Role of Nitric Oxide-Derived Metabolites in Reactions of Methylglyoxal with Lysine and Lysine-Rich Protein Leghemoglobin
por: Shumaev, Konstantin B., et al.
Publicado: (2022)

Oxidative damage of DNA induced by the reaction of methylglyoxal with lysine in the presence of ferritin
por: An, Sung Ho, et al.
Publicado: (2013)

Corrigendum to “Chitosan Prevents Gentamicin-Induced Nephrotoxicity via a Carbonyl Stress-Dependent Pathway”
por: Chou, Chu-Kuang, et al.
Publicado: (2017)

Upregulation of Transglutaminase and ε (γ-Glutamyl)-Lysine in the Fisher-Lewis Rat Model of Chronic Allograft Nephropathy
por: Shrestha, Badri, et al.
Publicado: (2014)

Mucoadhesive Rifampicin-Liposomes for the Treatment of Pulmonary Infection by Mycobacterium abscessus: Chitosan or ε-Poly-L-Lysine Decoration
por: Forte, Jacopo, et al.
Publicado: (2023)

The effects of low-dose Nepsilon-(carboxymethyl)lysine (CML) and Nepsilon-(carboxyethyl)lysine (CEL), two main glycation free adducts considered as potential uremic toxins, on endothelial progenitor cell function
por: Zhu, Jinzhou, et al.
Publicado: (2012)

N-(β-Carboxyethyl)-α-isoleucine
por: Nehls, Irene, et al.
Publicado: (2013)

Methylglyoxal Levels in Human Colorectal Precancer and Cancer: Analysis of Tumor and Peritumor Tissue
por: Chou, Chu-Kuang, et al.
Publicado: (2021)

Enhanced ε-Poly-L-Lysine Production by the Synergistic Effect of ε-Poly-L-Lysine Synthetase Overexpression and Citrate in Streptomyces albulus
por: Wang, Aixia, et al.
Publicado: (2020)

New chemosynthetic route to linear ε-poly-lysine
por: Tao, Youhua, et al.
Publicado: (2015)

Isoferulic acid prevents methylglyoxal-induced protein glycation and DNA damage by free radical scavenging activity
por: Meeprom, Aramsri, et al.
Publicado: (2015)

Scavenging neurotoxic aldehydes using lysine carbon dots
por: Bloch, Daniel Nir, et al.
Publicado: (2023)

Chitosan Prevents Gentamicin-Induced Nephrotoxicity via a Carbonyl Stress-Dependent Pathway
por: Chou, Chu-Kung, et al.
Publicado: (2015)

4-[(2-Carboxyethyl)amino]benzoic acid monohydrate
por: Jia, Chunman, et al.
Publicado: (2012)

Polyanionic Carboxyethyl Peptide Nucleic Acids (ce-PNAs): Synthesis and DNA Binding
por: Kirillova, Yuliya, et al.
Publicado: (2015)

Cysteine carboxyethylation: a novel post-translational modification associated with autoimmune arthritis
por: Didonna, Alessandro
Publicado: (2023)

Signaling molecule glutamic acid initiates the expression of genes related to methylglyoxal scavenging and osmoregulation systems in maize seedlings
por: Qiu, Xue-Mei, et al.
Publicado: (2021)

Methylglyoxal-Scavenging Enzyme Activities Trigger Erythroascorbate Peroxidase and Cytochrome c Peroxidase in Glutathione-Depleted Candida albicans
por: Kang, Sa-Ouk, et al.
Publicado: (2021)

Early Progression of Diabetic Nephropathy Correlates With Methylglyoxal-Derived Advanced Glycation End Products
por: Beisswenger, Paul J., et al.
Publicado: (2013)

Therapeutic Potential of Lespedeza bicolor to Prevent Methylglyoxal-Induced Glucotoxicity in Familiar Diabetic Nephropathy
por: Do, Moon Ho, et al.
Publicado: (2019)

Nanofabrication of methylglyoxal with chitosan biopolymer: a potential tool for enhancement of its anticancer effect
por: Pal, Aparajita, et al.
Publicado: (2015)

Substituting N(ε)-thioacetyl-lysine for N(ε)-acetyl-lysine in Peptide Substrates as a General Approach to Inhibiting Human NAD(+)-dependent Protein Deacetylases
por: Fatkins, David G., et al.
Publicado: (2008)

Formation and Inhibition of N(ε)-(Carboxymethyl)lysine in Saccharide-Lysine Model Systems during Microwave Heating
por: Li, Lin, et al.
Publicado: (2012)

Histone Lysine Methylation in Diabetic Nephropathy
por: Sun, Guang-dong, et al.
Publicado: (2014)

Analyzing structural alterations of mitochondrial intermembrane space superoxide scavengers cytochrome-c and SOD1 after methylglyoxal treatment
por: Mercado-Uribe, Hilda, et al.
Publicado: (2020)

Redetermined crystal structure of N-(β-carboxyethyl)-α-isoleucine
por: Chandrarekha, M., et al.
Publicado: (2015)

N(ε)-Carboxymethyl Modification of Lysine Residues in Pathogenic Prion Isoforms
por: Choi, Yeong-Gon, et al.
Publicado: (2015)

Major anthocyanins in elderberry effectively trap methylglyoxal and reduce cytotoxicity of methylglyoxal in HepG2 cell line
por: Ferreira, Sandrine S., et al.
Publicado: (2022)

Photo Cross‐Linking Probes Containing ϵ‐N‐Thioacyllysine and ϵ‐N‐Acyl‐(δ‐aza)lysine Residues
por: Bæk, Michael, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_n4gld7bch0dj8kmi3j99bu6obl