Soluble CLEC2 Extracellular Domain Improves Glucose and Lipid Homeostasis by Regulating Liver Kupffer Cell Polarization

The polarization of tissue resident macrophages toward the alternatively activated, anti-inflammatory M2 phenotype is believed to positively impact obesity and insulin resistance. Here we show that the soluble form of the extracellular domain (ECD) of C-type lectin-like receptor 2, CLEC2, regulates...

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Detalles Bibliográficos
Autores principales: Wu, Xinle, Zhang, Jun, Ge, Hongfei, Gupte, Jamila, Baribault, Helene, Lee, Ki Jeong, Lemon, Bryan, Coberly, Suzanne, Gong, Yan, Pan, Zheng, Rulifson, Ingrid C., Gardner, Jonitha, Richards, William G., Li, Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4489977/
https://www.ncbi.nlm.nih.gov/pubmed/26151067
http://dx.doi.org/10.1016/j.ebiom.2015.02.013

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