A microfluidic device for label-free, physical capture of circulating tumor cell-clusters

Cancer cells metastasize through the bloodstream either as single migratory circulating tumor cells (CTCs) or as multicellular groupings (CTC-clusters). Existing technologies for CTC enrichment are designed primarily to isolate single CTCs, and while CTC-clusters are detectable in some cases, their...

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Detalles Bibliográficos
Autores principales: Sarioglu, A. Fatih, Aceto, Nicola, Kojic, Nikola, Donaldson, Maria C., Zeinali, Mahnaz, Hamza, Bashar, Engstrom, Amanda, Zhu, Huili, Sundaresan, Tilak K., Miyamoto, David T., Luo, Xi, Bardia, Aditya, Wittner, Ben S., Ramaswamy, Sridhar, Shioda, Toshi, Ting, David T., Stott, Shannon L., Kapur, Ravi, Maheswaran, Shyamala, Haber, Daniel A., Toner, Mehmet
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4490017/
https://www.ncbi.nlm.nih.gov/pubmed/25984697
http://dx.doi.org/10.1038/nmeth.3404

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