Intravaginal HPV DNA vaccination with electroporation induces local CD8+ T-cell immune responses and antitumor effects against cervicovaginal tumors

Therapeutic human papillomavirus (HPV) vaccines have the potential to inhibit the progression of an established HPV infection to precancer and cancer lesions by targeting HPV oncoproteins. We have previously developed a therapeutic DNA vaccine encoding calreticulin (CRT) linked to E7, CRT/E7 DNA vac...

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Detalles Bibliográficos
Autores principales: Sun, Y, Peng, S, Qiu, J, Miao, J, Yang, B, Jeang, J, Hung, C-F, Wu, T-C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4490060/
https://www.ncbi.nlm.nih.gov/pubmed/25786869
http://dx.doi.org/10.1038/gt.2015.17

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4490060/
https://www.ncbi.nlm.nih.gov/pubmed/25786869
http://dx.doi.org/10.1038/gt.2015.17

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