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Traction microscopy to identify force modulation in sub-resolution adhesions
We present a reconstruction algorithm that resolves cellular tractions in diffraction-limited nascent adhesions (NAs). The enabling method is the introduction of sparsity regularization to the solution of the inverse problem, which suppresses noise without underestimating traction magnitude. We show...
Autores principales: | Han, Sangyoon J., Oak, Youbean, Groisman, Alex, Danuser, Gaudenz |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4490115/ https://www.ncbi.nlm.nih.gov/pubmed/26030446 http://dx.doi.org/10.1038/nmeth.3430 |
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