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IGF-1 Receptor and Adhesion Signaling: An Important Axis in Determining Cancer Cell Phenotype and Therapy Resistance

IGF-1R expression and activation levels generally cannot be correlated in cancer cells, suggesting that cellular proteins may modulate IGF-1R activity. Strong candidates for such modulation are found in cell-matrix and cell–cell adhesion signaling complexes. Activated IGF-1R is present at focal adhe...

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Detalles Bibliográficos
Autores principales:	Cox, Orla T., O’Shea, Sandra, Tresse, Emilie, Bustamante-Garrido, Milan, Kiran-Deevi, Ravi, O’Connor, Rosemary
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2015
Materias:	Endocrinology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4490239/ https://www.ncbi.nlm.nih.gov/pubmed/26191041 http://dx.doi.org/10.3389/fendo.2015.00106

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