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Magnetic Resonance Techniques Applied to the Diagnosis and Treatment of Parkinson’s Disease

Parkinson’s disease (PD) affects at least 10 million people worldwide. It is a neurodegenerative disease, which is currently diagnosed by neurological examination. No neuroimaging investigation or blood biomarker is available to aid diagnosis and prognosis. Most effort toward diagnosis using magneti...

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Autores principales: de Celis Alonso, Benito, Hidalgo-Tobón, Silvia S., Menéndez-González, Manuel, Salas-Pacheco, José, Arias-Carrión, Oscar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4490248/
https://www.ncbi.nlm.nih.gov/pubmed/26191037
http://dx.doi.org/10.3389/fneur.2015.00146
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author de Celis Alonso, Benito
Hidalgo-Tobón, Silvia S.
Menéndez-González, Manuel
Salas-Pacheco, José
Arias-Carrión, Oscar
author_facet de Celis Alonso, Benito
Hidalgo-Tobón, Silvia S.
Menéndez-González, Manuel
Salas-Pacheco, José
Arias-Carrión, Oscar
author_sort de Celis Alonso, Benito
collection PubMed
description Parkinson’s disease (PD) affects at least 10 million people worldwide. It is a neurodegenerative disease, which is currently diagnosed by neurological examination. No neuroimaging investigation or blood biomarker is available to aid diagnosis and prognosis. Most effort toward diagnosis using magnetic resonance (MR) has been focused on the use of structural/anatomical neuroimaging and diffusion tensor imaging (DTI). However, deep brain stimulation, a current strategy for treating PD, is guided by MR imaging (MRI). For clinical prognosis, diagnosis, and follow-up investigations, blood oxygen level-dependent MRI, DTI, spectroscopy, and transcranial magnetic stimulation have been used. These techniques represent the state of the art in the last 5 years. Here, we focus on MR techniques for the diagnosis and treatment of Parkinson’s disease.
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spelling pubmed-44902482015-07-17 Magnetic Resonance Techniques Applied to the Diagnosis and Treatment of Parkinson’s Disease de Celis Alonso, Benito Hidalgo-Tobón, Silvia S. Menéndez-González, Manuel Salas-Pacheco, José Arias-Carrión, Oscar Front Neurol Neuroscience Parkinson’s disease (PD) affects at least 10 million people worldwide. It is a neurodegenerative disease, which is currently diagnosed by neurological examination. No neuroimaging investigation or blood biomarker is available to aid diagnosis and prognosis. Most effort toward diagnosis using magnetic resonance (MR) has been focused on the use of structural/anatomical neuroimaging and diffusion tensor imaging (DTI). However, deep brain stimulation, a current strategy for treating PD, is guided by MR imaging (MRI). For clinical prognosis, diagnosis, and follow-up investigations, blood oxygen level-dependent MRI, DTI, spectroscopy, and transcranial magnetic stimulation have been used. These techniques represent the state of the art in the last 5 years. Here, we focus on MR techniques for the diagnosis and treatment of Parkinson’s disease. Frontiers Media S.A. 2015-07-03 /pmc/articles/PMC4490248/ /pubmed/26191037 http://dx.doi.org/10.3389/fneur.2015.00146 Text en Copyright © 2015 de Celis Alonso, Hidalgo-Tobón, Menéndez-González, Salas-Pacheco and Arias-Carrión. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Neuroscience
de Celis Alonso, Benito
Hidalgo-Tobón, Silvia S.
Menéndez-González, Manuel
Salas-Pacheco, José
Arias-Carrión, Oscar
Magnetic Resonance Techniques Applied to the Diagnosis and Treatment of Parkinson’s Disease
title Magnetic Resonance Techniques Applied to the Diagnosis and Treatment of Parkinson’s Disease
title_full Magnetic Resonance Techniques Applied to the Diagnosis and Treatment of Parkinson’s Disease
title_fullStr Magnetic Resonance Techniques Applied to the Diagnosis and Treatment of Parkinson’s Disease
title_full_unstemmed Magnetic Resonance Techniques Applied to the Diagnosis and Treatment of Parkinson’s Disease
title_short Magnetic Resonance Techniques Applied to the Diagnosis and Treatment of Parkinson’s Disease
title_sort magnetic resonance techniques applied to the diagnosis and treatment of parkinson’s disease
topic Neuroscience
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4490248/
https://www.ncbi.nlm.nih.gov/pubmed/26191037
http://dx.doi.org/10.3389/fneur.2015.00146
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