Cargando…
Connecting SNPs in Diabetes: A Spatial Analysis of Meta-GWAS Loci
Meta-analyses of genome-wide association studies (GWAS) have improved our understanding of the genetic foundations of a number of diseases, including diabetes. However, single nucleotide polymorphisms (SNPs) that are identified by GWAS, especially those that fall outside of gene regions, do not alwa...
Autores principales: | Schierding, William, O’Sullivan, Justin M. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4490250/ https://www.ncbi.nlm.nih.gov/pubmed/26191039 http://dx.doi.org/10.3389/fendo.2015.00102 |
Ejemplares similares
-
Physical Interactions and Expression Quantitative Traits Loci Identify Regulatory Connections for Obesity and Type 2 Diabetes Associated SNPs
por: Fadason, Tayaza, et al.
Publicado: (2017) -
Chromatin interactions and expression quantitative trait loci reveal genetic drivers of multimorbidities
por: Fadason, Tayaza, et al.
Publicado: (2018) -
GWAS SNPs Impact Shared Regulatory Pathways Amongst Multimorbid Psychiatric Disorders and Cognitive Functioning
por: Golovina, Evgeniia, et al.
Publicado: (2020) -
Spatially constrained gene regulation identifies key genetic contributions of preeclampsia, hypertension, and proteinuria
por: Boom, Genevieve, et al.
Publicado: (2023) -
Analysis of the joint effect of SNPs to identify independent loci and allelic heterogeneity in schizophrenia GWAS data
por: Polushina, Tatiana, et al.
Publicado: (2017)