The glucagon-like peptide-1 receptor as a potential treatment target in alcohol use disorder: evidence from human genetic association studies and a mouse model of alcohol dependence

The hormone glucagon-like peptide-1 (GLP-1) regulates appetite and food intake. GLP-1 receptor (GLP-1R) activation also attenuates the reinforcing properties of alcohol in rodents. The present translational study is based on four human genetic association studies and one preclinical study providing...

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Detalles Bibliográficos
Autores principales: Suchankova, P, Yan, J, Schwandt, M L, Stangl, B L, Caparelli, E C, Momenan, R, Jerlhag, E, Engel, J A, Hodgkinson, C A, Egli, M, Lopez, M F, Becker, H C, Goldman, D, Heilig, M, Ramchandani, V A, Leggio, L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4490279/
https://www.ncbi.nlm.nih.gov/pubmed/26080318
http://dx.doi.org/10.1038/tp.2015.68

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4490279/
https://www.ncbi.nlm.nih.gov/pubmed/26080318
http://dx.doi.org/10.1038/tp.2015.68

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