Acute and chronic stress differentially regulate cyclin-dependent kinase 5 in mouse brain: implications to glucocorticoid actions and major depression

Stress activates the hypothalamic–pituitary–adrenal axis, which in turn increases circulating glucocorticoid concentrations and stimulates the glucocorticoid receptor (GR). Chronically elevated glucocorticoids by repetitive exposure to stress are implicated in major depression and anxiety disorders....

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Detalles Bibliográficos
Autores principales: Papadopoulou, A, Siamatras, T, Delgado-Morales, R, Amin, N D, Shukla, V, Zheng, Y-L, Pant, H C, Almeida, O F X, Kino, T
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4490283/
https://www.ncbi.nlm.nih.gov/pubmed/26057048
http://dx.doi.org/10.1038/tp.2015.72

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