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Machine learning plus optical flow: a simple and sensitive method to detect cardioactive drugs

Current preclinical screening methods do not adequately detect cardiotoxicity. Using human induced pluripotent stem cell-derived cardiomyocytes (iPS-CMs), more physiologically relevant preclinical or patient-specific screening to detect potential cardiotoxic effects of drug candidates may be possibl...

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Detalles Bibliográficos
Autores principales: Lee, Eugene K., Kurokawa, Yosuke K., Tu, Robin, George, Steven C., Khine, Michelle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4490343/
https://www.ncbi.nlm.nih.gov/pubmed/26139150
http://dx.doi.org/10.1038/srep11817