The Neurocognitive Profile of the Cerebellum in Multiple Sclerosis

In recent years, a high number of studies have demonstrated that neuropsychological functions are altered in multiple sclerosis (MS) patients with cerebellar lesions, mainly including attention, working memory and verbal fluency. Since the present literature is often elusive on this topic, we aim to...

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Detalles Bibliográficos
Autores principales: Sarica, Alessia, Cerasa, Antonio, Quattrone, Aldo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4490438/
https://www.ncbi.nlm.nih.gov/pubmed/26030676
http://dx.doi.org/10.3390/ijms160612185
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author Sarica, Alessia
Cerasa, Antonio
Quattrone, Aldo
author_facet Sarica, Alessia
Cerasa, Antonio
Quattrone, Aldo
author_sort Sarica, Alessia
collection PubMed
description In recent years, a high number of studies have demonstrated that neuropsychological functions are altered in multiple sclerosis (MS) patients with cerebellar lesions, mainly including attention, working memory and verbal fluency. Since the present literature is often elusive on this topic, we aim to provide a comprehensive report about the real impact of cerebellar damages (evaluated as volume, lesions or connectivity measures) on cognitive functions. In particular in this review, we report and discuss recent works from 2009 to 2015, which have demonstrated the key role of the cerebellum in cognitive impairment of MS patients.
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spelling pubmed-44904382015-07-07 The Neurocognitive Profile of the Cerebellum in Multiple Sclerosis Sarica, Alessia Cerasa, Antonio Quattrone, Aldo Int J Mol Sci Review In recent years, a high number of studies have demonstrated that neuropsychological functions are altered in multiple sclerosis (MS) patients with cerebellar lesions, mainly including attention, working memory and verbal fluency. Since the present literature is often elusive on this topic, we aim to provide a comprehensive report about the real impact of cerebellar damages (evaluated as volume, lesions or connectivity measures) on cognitive functions. In particular in this review, we report and discuss recent works from 2009 to 2015, which have demonstrated the key role of the cerebellum in cognitive impairment of MS patients. MDPI 2015-05-28 /pmc/articles/PMC4490438/ /pubmed/26030676 http://dx.doi.org/10.3390/ijms160612185 Text en © 2015 by the authors; licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Sarica, Alessia
Cerasa, Antonio
Quattrone, Aldo
The Neurocognitive Profile of the Cerebellum in Multiple Sclerosis
title The Neurocognitive Profile of the Cerebellum in Multiple Sclerosis
title_full The Neurocognitive Profile of the Cerebellum in Multiple Sclerosis
title_fullStr The Neurocognitive Profile of the Cerebellum in Multiple Sclerosis
title_full_unstemmed The Neurocognitive Profile of the Cerebellum in Multiple Sclerosis
title_short The Neurocognitive Profile of the Cerebellum in Multiple Sclerosis
title_sort neurocognitive profile of the cerebellum in multiple sclerosis
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4490438/
https://www.ncbi.nlm.nih.gov/pubmed/26030676
http://dx.doi.org/10.3390/ijms160612185
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