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Combinatorial Pharmacophore-Based 3D-QSAR Analysis and Virtual Screening of FGFR1 Inhibitors

The fibroblast growth factor/fibroblast growth factor receptor (FGF/FGFR) signaling pathway plays crucial roles in cell proliferation, angiogenesis, migration, and survival. Aberration in FGFRs correlates with several malignancies and disorders. FGFRs have proved to be attractive targets for therape...

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Detalles Bibliográficos
Autores principales:	Zhou, Nannan, Xu, Yuan, Liu, Xian, Wang, Yulan, Peng, Jianlong, Luo, Xiaomin, Zheng, Mingyue, Chen, Kaixian, Jiang, Hualiang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2015
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4490501/ https://www.ncbi.nlm.nih.gov/pubmed/26110383 http://dx.doi.org/10.3390/ijms160613407

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