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Reducing the Oxidation Level of Dextran Aldehyde in a Chitosan/Dextran-Based Surgical Hydrogel Increases Biocompatibility and Decreases Antimicrobial Efficacy

A highly oxidized form of a chitosan/dextran-based hydrogel (CD-100) containing 80% oxidized dextran aldehyde (DA-100) was developed as a post-operative aid, and found to significantly prevent adhesion formation in endoscopic sinus surgery (ESS). However, the CD-100 hydrogel showed moderate in vitro...

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Detalles Bibliográficos
Autores principales: Chan, Maggie, Brooks, Heather J. L., Moratti, Stephen C., Hanton, Lyall R., Cabral, Jaydee D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4490524/
https://www.ncbi.nlm.nih.gov/pubmed/26086827
http://dx.doi.org/10.3390/ijms160613798