Dimethyl Fumarate Protects Neural Stem/Progenitor Cells and Neurons from Oxidative Damage through Nrf2-ERK1/2 MAPK Pathway

Multiple sclerosis (MS) is the most common multifocal inflammatory demyelinating disease of the central nervous system (CNS). Due to the progressive neurodegenerative nature of MS, developing treatments that exhibit direct neuroprotective effects are needed. Tecfidera™ (BG-12) is an oral formulation...

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Detalles Bibliográficos
Autores principales: Wang, Qin, Chuikov, Sergei, Taitano, Sophina, Wu, Qi, Rastogi, Arjun, Tuck, Samuel J., Corey, Joseph M., Lundy, Steven K., Mao-Draayer, Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4490529/
https://www.ncbi.nlm.nih.gov/pubmed/26090715
http://dx.doi.org/10.3390/ijms160613885

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