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System-wide identification of wild-type SUMO-2 conjugation sites
SUMOylation is a reversible post-translational modification (PTM) regulating all nuclear processes. Identification of SUMOylation sites by mass spectrometry (MS) has been hampered by bulky tryptic fragments, which thus far necessitated the use of mutated SUMO. Here we present a SUMO-specific proteas...
Autores principales: | Hendriks, Ivo A., D'Souza, Rochelle C., Chang, Jer-Gung, Mann, Matthias, Vertegaal, Alfred C. O. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Pub. Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4490555/ https://www.ncbi.nlm.nih.gov/pubmed/26073453 http://dx.doi.org/10.1038/ncomms8289 |
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