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Glutamate dehydrogenase is a novel prognostic marker and predicts metastases in colorectal cancer patients
BACKGROUND: Glutamate dehydrogenase (GDH) is a key enzyme that catalyzes the final reaction of the glutamine metabolic pathway, and has been reported implicated in tumor growth and metastasis. However, it’s clinical significance and role in colorectal cancer (CRC) pathogenesis is largely unknown. ME...
Autores principales: | , , , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4490642/ https://www.ncbi.nlm.nih.gov/pubmed/25947346 http://dx.doi.org/10.1186/s12967-015-0500-6 |