Genetic Differences in the Immediate Transcriptome Response to Stress Predict Risk-Related Brain Function and Psychiatric Disorders

Depression risk is exacerbated by genetic factors and stress exposure; however, the biological mechanisms through which these factors interact to confer depression risk are poorly understood. One putative biological mechanism implicates variability in the ability of cortisol, released in response to...

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Detalles Bibliográficos
Autores principales: Arloth, Janine, Bogdan, Ryan, Weber, Peter, Frishman, Goar, Menke, Andreas, Wagner, Klaus V., Balsevich, Georgia, Schmidt, Mathias V., Karbalai, Nazanin, Czamara, Darina, Altmann, Andre, Trümbach, Dietrich, Wurst, Wolfgang, Mehta, Divya, Uhr, Manfred, Klengel, Torsten, Erhardt, Angelika, Carey, Caitlin E., Conley, Emily Drabant, Ruepp, Andreas, Müller-Myhsok, Bertram, Hariri, Ahmad R., Binder, Elisabeth B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4490780/
https://www.ncbi.nlm.nih.gov/pubmed/26050039
http://dx.doi.org/10.1016/j.neuron.2015.05.034

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