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Secreted miR-34a in astrocytic shedding vesicles enhanced the vulnerability of dopaminergic neurons to neurotoxins by targeting Bcl-2

MicroRNAs (miRNAs) are a class of noncoding RNAs that regulates target gene expression at posttranscriptional level, leading to further biological functions. We have demonstrated that microvesicles (MVs) can deliver miRNAs into target cells as a novel way of intercellular communication. It is report...

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Detalles Bibliográficos
Autores principales: Mao, Susu, Sun, Qi, Xiao, Hui, Zhang, Chenyu, Li, Liang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Higher Education Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4491052/
https://www.ncbi.nlm.nih.gov/pubmed/26091620
http://dx.doi.org/10.1007/s13238-015-0168-y