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Two TRPV1 receptor antagonists are effective in two different experimental models of migraine

BACKGROUND: The capsaicin and heat responsive ion channel TRPV1 is expressed on trigeminal nociceptive neurons and has been implicated in the pathophysiology of migraine attacks. Here we investigate the efficacy of two TRPV1 channel antagonists in blocking trigeminal activation using two in vivo mod...

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Detalles Bibliográficos
Autores principales:	Meents, Jannis E, Hoffmann, Jan, Chaplan, Sandra R, Neeb, Lars, Schuh-Hofer, Sigrid, Wickenden, Alan, Reuter, Uwe
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer Milan 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4491068/ https://www.ncbi.nlm.nih.gov/pubmed/26109436 http://dx.doi.org/10.1186/s10194-015-0539-z

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